THE INCIDENCE AND PROFILE OF CARDIOTROPIC VIRAL ANTIGENS IN THE MYOCARDIUM IN PATIENTS WITH DECOMPENSATED CHRONIC HEART FAILURE WITH SYSTOLIC DYSFUNCTION OF ISCHEMIC ORIGIN
https://doi.org/10.29001/2073-8552-2017-32-1-46-49
Abstract
This article presents the results of examination and treatment of 12 patients with decompensated chronic heart failure (CHF). The heart cellular composition and profile of viruses in the myocardial tissue were studied in patients hospitalized to the Cardiology Research Institute in Tomsk during the period from 2015 to 2016. Study showed the frequencies of inflammation and the presence of viruses in the myocardium in patients with coronary heart disease (CHD) and decompensated CHF.
About the Authors
E. V. Kruchinkina
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
National Research Tomsk State University
Russian Federation
Russian Federation
T. R. Ryabova
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Yu. V. Rogovskaya
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
National Research Tomsk State University
Russian Federation
Russian Federation
R. E. Batalov
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
National Research Tomsk State University
Russian Federation
Russian Federation
V. V. Ryabov
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
National Research Tomsk State University
Siberian State Medical University
Russian Federation
Russian Federation
References
1. Miro O., Peacock F.W., McMurray J.J. et al. European Society of Cardiology– Acute Cardiovascular Care Association position paper on safe discharge of acute heart failure patients from the emergency department // Eur. Heart J.: Acute Cardiovasc. Care. – 2016. – Vol. 10. – P. 1–10.
2. Агеев Ф.Т., Овчинников А.Г. Новые рекомендации по диагностике сердечной недостаточности с сохраненной фракцией выброса ЛЖ (диастолической сердечной недостаточности) // Сердечн. недостат. – 2013. – № 5. – С. 297–300.
3. Мареев В.Ю., Агеев Ф.Т., Арутюнов Г.П. и др. Национальные рекомендации ОССН, РКО и РНМОТ по диагностике и лечению ХСН (четвертый пересмотр) // Сердечн. недостат. – 2013. – № 7. – С. 379–472.
4. Козырев О.А., Никонорова И.В. Нейроэндокринные соотношения у женщин с хронической сердечной недостаточности // Вестн. нов. мед. технологий. Электронный журнал. – 2015. – № 3. – С. 1–5.
5. Маслов Л.Н., Рябов В.В., Сазонова С.И. Клеточная трансплантация в лечении инфаркта миокарда: проблемы и перспективы // Вестн. трансплантологии и искусственных органов (Москва). – 2003. – № 4. – C. 78–86.
6. Оганов Р.Г. Новые возможности улучшения качества и продолжительности жизни больных стабильной ишемической болезнью сердца // Атмосфера. Новости кардиологии. – 2015. – № 1. – С. 11–13.
7. Thomsen M.M., Lewinter Ch., Kober L. Varying effects of recommended treatments for heart failure with reduced ejection fraction: meta-analysis of randomized controlled trials in the ESC and ACCF/AHA guidelines // ESC Heart Failure. – 2016. – Vol. 10. – P. 1–10.
8. Hobbs F.D., Roalfe A.K., Davis R.C. et al. Research Practices Consortium (MidReC). Prognosis of all cause heart failure and borderline left ventricular systolic dysfunction: 5 year mortality follow-up of the Echocardiographic Heart of England Screening Study (ECHOES) // Eur. Heart J. – 2007. – Vol. 28, No. 6. – P. 1128–1134.
9. Roger V.L. Epidemiology of heart failure // NIH Public Access. – 2013. – Vol. 113, No. 6. – P. 646–659.
10. Rogovskaya Yu., Botalov R., Ryabov V. et al. Role of inflammation, viruses and tissue macrophages in the development of idiopathic arrhythmia and heart failure // Key Engineering Materials. – 2016. – Vol. 683. – P. 487–492.
11. Ковалева О.Н. Коррекция цитокиновой агрессии при сердечной недостаточности: теоретические предпосылки и практические реалии // Сердечн. недостат. – 2011. – № 2. – С. 93–100.
12. Briasoulis A., Androulakis E., Christophides Th. et al. The role of inflammation and cell death in the pathogenesis, progression and treatment of heart failure // Heart Fail. Rev. – 2016. – Vol. 21, No. 2. – P. 169–176.
13. Гомбожапова А.Э., Роговская Ю.В., Рябова Т.Р. и др. Случай псевдокоронарного варианта клинического течения воспалительной вирусной кардиомиопатии // Сиб. мед. журн. (Томск). – 2015. – Т. 30, № 4. – С. 60–65.
14. Ryabov V.V., Kruchinkina E.V., Rogovskaya Yu.V. et al. Clinical and morphological characteristics of chronic inflammation in the myocardium in patients with decompensated chronic heart failure accompanied by ischemic systolic dysfunction: study protocol for an open-label nonrandomized trial // Clinic. Trials in Degenerative Diseases. – 2016. – No. 4. – In press.
15. Caforio A.L.P., Pankuweit S., Arbustini E. et al. Current state of knowledge on a etiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases // Eur. Heart J. – 2013. – Vol. 34. – P. 2636–2648.
16. Харченко Е.П. Сердечная недостаточность: патогенетический континуум и биомаркеры // Кардиология. – 2012. – № 3. – С. 53–64.
17. Костенко В.А., Ариcкина О.Б., Осипова И.В. и др. Элементы системного воспалительного ответа и клинические параллели у пациентов с декомпенсированной хронической сердечной недостаточностью // Сиб. мед. журн. (Томск). – 2014. – Т. 29, № 3. – С. 37–40.
18. Goonewardena S.N., Stein A.B., Tsuchida R.E. et al. Monocyte subsets and inflammatory cytokines in acute decompensated heart failure // J. Cardiac Fail. – 2016. – Vol. 22, No. 5. – P. 358– 365.
Review
For citations:
Kruchinkina E.V., Ryabova T.R., Rogovskaya Yu.V., Batalov R.E., Ryabov V.V. THE INCIDENCE AND PROFILE OF CARDIOTROPIC VIRAL ANTIGENS IN THE MYOCARDIUM IN PATIENTS WITH DECOMPENSATED CHRONIC HEART FAILURE WITH SYSTOLIC DYSFUNCTION OF ISCHEMIC ORIGIN. Siberian Journal of Clinical and Experimental Medicine. 2017;32(1):46-49. (In Russ.) https://doi.org/10.29001/2073-8552-2017-32-1-46-49
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